Research

Vision:

Enable clinical research that directly benefits patients who require endocrine, diabetic and thyroid care.

Mission:

Empower research based clinical care and enable the identification of disease progressive biomarkers, in endocrine, thyroid and pancreatic cancers.

Funded Projects:

  1. RSSDI: Determination of the diagnostic/ prognostic significance of CaMKK2 in postmenopausal diabetic osteoporosis patients treated with Pioglitazone (thiazolidinedione), Dapagliflozin (SGLT2 inhibitor).
  2. ESTN: "Molecular Diagnosis of TCF7L2 gene Polymorphisms and insulin dependency in T2DM patients of south Indian Population."
  3. ESTN: "Molecular Diagnosis of TCF7L2 gene Polymorphisms and differential drug
  4. DBT: "Epigenetic regulation of GIPR (Glucose Dependent Insulinotropic Hormone Receptor) signaling and its influence on therapeutic responses in MODY3 Patients".
  5. RSSDI Student grant: Influence of THADA Polymorphisms on T2DM, Metabolic Syndrome and PCOS.

Project of interest being pursued:

  1. Molecular Diagnosis of Congenital Adrenal Hyperplasia
  2. Prevalence and Clinical Relevance of GCK Mutations (GCKMODY/ MODY3), HNF-1α Mutations (HNF-1α MODY2, MODY3) In South Tamil Nadu, India.
  3. Incidence of TCF7, TCF7L2 polymorphisms in the type 1 diabetes patient population of south Tamil Nadu, India.
  4. Molecular Diagnosis of MODY 12 (ABCC8).
  5. Development of improvised non-invasive qualitative, quantitative glucose monitoring tattoo for T2DM patients". (in collaboration with Dr. V.S. Vasantha, Materials Science Department, School of Chemistry, MKU, Madurai).
  6. Molecular Diagnosis of SNPs associated with PCOS in south Indian Women.

Faculty and Research Staff Members

  1. Dr. Kumaravel Velayutham, MBBS., MD., DNB (Endo).
    Director – Research
  2. Dr. Rohini Gomathinayagam PhD.
    Senior Scientist & Head of Research
  3. Mr. R. Balaji M.Sc (Biotechnology).
    M.Phil (Nano & Neuro Toxicology). Research Associate
  4. Miss. M. Jeyasudha M.Sc (Microbiology)
    Ph.D Scholar

Collaborators:

  1. Dr. G. Kumaresan, PhD
    Professor & Head,
    Department of Genetics,
    Madurai Kamaraj University,
    Madurai - 625021
  2. Dr.V.S.Vasantha, PhD
    Professor & Head,
    Department of Natural Products Chemistry,
    Madurai Kamaraj University,
    Madurai - 625021
  3. Dr.Balamurugan Appakalai, PhD
    Associate Professor of Surgery,
    Director, Clinical Islet Cell Laboratory,
    Cardiovascular Innovation Institute,
    Scientific Director, Islet biology and transplantation program,
    University of Louisville, Louisville, KY,40202.
  4. Dr.R.Sarojini, M.D
    Professor,
    K.A.P. Viswanatham Government Medical College,
    Periyamilaguparai,
    Collector office Road,
    Trichy
    Tamil Nadu - 620001.

Department of Molecular Genetics: